Bristol ENDOTHELIAL Meeting 2019
19 September 2019
SPONSORED by:
WELCOME
ORGANIZER:
Dr Camilla Cerutti
University of Bristol
EMAIL: camilla.cerutti@bristol.ac.uk
SCOPE
The purpose of the one day Bristol ENDOTHELIAL meeting is to bridge
all the researchers within the University of Bristol working
on vasculature and endothelial cells, from basic to clinical research, to foster cross-disciplinary exchange of ideas and expertise to create a Vascular Endothelium Network @UoB
The focus of the meeting is to promote collaborations and
networking on the vasculature/endothelium themes across
Faculties and Schools @UoB to increase research impact.
The meeting will give the opportunity to showcase the vascular/endothelium research @UoB
across disciplines presenting techniques/sample availability/cell types and tools on top of science.
FORMAT
The meeting format will have 5, 10, 15 minutes TALKS and a POSTER session.
I am eager to have as many early career researcher as possible
to attend and present their research and techniques.
I encourage group leaders, professors and endothelial cell passionate to participate to the meeting and promote the Bristol ENDOTHELIAL meeting within their group/colleagues.
I hope you will enjoy this great day of science!
Connect
Tweet about the Bristol ENDOTHELIAL meeting (BEM2019) @BEM20191
TIME & PLACE
WHEN: 19 SEPTEMBER 2019
TIME: 8:30-5:30
WHERE: The FOUNDATION-space event
St George’s Road at the corner with Deanery Road (see the MAP below)
Bristol,BS1 5AF
(150m from College green bus stop- 100m from the Cathedral)
PUBLIC TRANSPORT: More information can be found at https://travelwest.info/
CAR: list of public car parks can be found at https://travelwest.info/drive/parking/bristol-car-parking-map
The closest car park is the College Street pay and display.
There is also on-street metered parking on Deanery Road.
MAP: The FOUNDATION St George’s Road. Bristol, BS1 5BE
PROGRAM
Download the PROGRAM
GUEST SPEAKERS
Dr Anjali Kusumbe `Organotypic angiocrine signals in health and disease`
University of Oxford
Medical science divisions Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences Kennedy Institute of Rheumatology
Anjali Kusumbe was trained in India. She joined the lab of Ralf Adams at the Max Planck Institute for Molecular Biomedicine in Munster as a postdoc fellow. She is currently principal investigator of the group “Tissue and tumor microenvironments” at the Kennedy Institute in Oxford, UK.
Her group is interested in exploring the contributions of the vasculature in defining the tissue microenvironments and unravelling the changes occurring in the vascular microenvironments during tumour growth. They seek to elucidate the angiocrine signals underlying the regional specialization of tissue microenvironments, and how these specialized vascular niches instruct cell fate and behavior in normal and tumour tissue.
KEY PUBLICATIONS:
Romeo SG, Alawi KM, Rodrigues J, Singh A, Kusumbe AP, Ramasamy SK.
Nat Cell Biol. 2019
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Kusumbe AP, Ramasamy SK, Itkin T, Mäe MA, Langen UH, Betsholtz C, Lapidot T, Adams RH.
Nature. 2016
Sample preparation for high-resolution 3D confocal imaging of mouse skeletal tissue.
Kusumbe AP, Ramasamy SK, Starsichova A, Adams RH.
Nat Protoc. 2015
Osteoclast progenitors promote bone vascularization and osteogenesis.
Kusumbe AP, Adams RH.
Nat Med. 2014
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone.
Kusumbe AP, Ramasamy SK, Adams RH.
Nature. 2014
Dr Alessandra Granata ' Modelling Small Vessel Disease and stroke using human induced Pluripotent Stem Cells’
University of Cambridge
Cambridge Cardiovascular
I lead the research group for modelling cerebrovascular diseases using patient-derived induced pluripotent stem cells (iPSC). I am based at the Clifford Allbutt Building, Central Biomedical Campus, Addenbrooke’s Site and am part of the Stroke Research Group of Professor Hugh Markus, in the department of Clinical Neurosciences.
My main research interest is to develop iPSC-based model system for genetic forms of cerebral small vessel diseases (SVD), exploiting findings from genome wide association studies (GWAS) and whole genome sequencing studies in ischaemic stroke. We believe that iPSC-derived models can be used to uncover disease mechanisms and to identify new treatments for SVD.
KEY PUBLICATIONS:
Granata A, Serrano F, Bernard WG, McNamara M, Low L, Sastry P, Sinha S. Nat Genet. 2017 Jan;49(1):97-109.
Temporal and embryonic lineage-dependent regulation of human vascular SMC development by NOTCH3.
Granata A, Bernard WG, Zhao N, Mccafferty J, Lilly B, Sinha S. Stem Cells Dev. 2015 Apr 1;24(7):846-56.
Sinha S, Iyer D, Granata A. Cell Mol Life Sci. 2014 Jun;71(12):2271-88.
SPEAKERS
Miss Rosaria Bianco
Effect of flow and angiotensin II on endothelial cells with relevance to aneurysm formation
Dr Andrew Bond
Blood outgrowth endothelial cells for tissue engineered vascular grafts
Arterial bioengineering
Eng Michele Carrabba
Development of Multi-layered Tissue Engineering Vascular Graft for small-diameter vascular replacement
Tissue Engineering Vascular Graft
human cell-seeded scaffolds
Dr Natalie Finch
Glomerular endothelial fenestrations
vascular endothelial
renal physiology
Dr Becky Foster
Bristol Renal: Models and techniques
vascular endothelial growth factor (VEGF)-A
podocyte biology
renal physiology
academic renal unit
proteins involved in glomerular physiology & pathology
Prof Sarah George
Acute endothelial cell inflammation and coronary artery vein graft disease.
NFkb
Wnt
inflammation
Dr Jason L Johnson
Regulatory role of IL-3 in angiogenesis and neovascularisation
vascular microRNAs
MMP
Miss Kirsty Lewis
Platelet-derived extracellular vesicles and platelet secretion in the regulation of endothelial function’
platelets
secretion
microvesicles
angiogenesis
Dr Scott Miners
Does breakdown in endothelial-pericyte communication underlie vascular dysfunction in Alzheimer's disease?
Pericytes
Alzheimer's disease
beta amyloid
hypoxia
Prof Harry Mellor
Endothelial cell secretion
Endothelial cell shape and movement
Endothelial cell receptor signalling and trafficking
Dr Elisa Pedone
Microfluidic-microscopy platform for ‘on-demand’ dynamic gene expression regulation and signaling pathway activity
Synthetic Biology
control theory
stem cell identity
Dr Raina Ramnath and Dr Yan Qiu
Diabetes and endothelial glycocalyx
vascular endothelial glycocalyx
diabetes
renal physiology
Miss Lien Reolizo
Anti-inflammatory effects of Hhex in endothelial cells
NFkb
inflammation
Dr Christopher Rice
Neutrophil extracellular traps (NETs) promote adhesion of infected red blood cell to vascular endothelium in malaria
Malaria,
Neutrophils
NETs
Dr Beck Richardson
Endothelial cells in cardiac repair and regeneration in adult zebrafish
wound healing
human disease
cardiovascular disease
Dr Tony Walsh
Platelet-derived extracellular vesicles and platelet secretion in the regulation of endothelial function’
platelets
secretion
microvesicles
angiogenesis
Dr Helen Weavers
Modelling immune cell extravasation from vessels to wounds using in vivo Drosophila and mouse models
immune cell extravasation
wound inflammation
Drosophila model
Mr Aaron Scott
In vivo characterisation of endothelial-derived extracellular vesicles in zebrafish
extracellular vescicles
BEM 2019 _event pictures
TALKS.
SPEAKERS- FACILITY
vascular and endothelial research
IMAGING FACILITY
Dr Mark Jepson Imaging Facility Manager
PROTEOMIC FACILITY
Dr Kate Heesom Proteomics Facility Manager
POSTER session
PREPARE you poster
There are not SIZE or ORIENTATION restrictions
Poster POSITION at BEM2019
- the poster AREA is located at the far end of the event space (entering turn left)
- please find a TAG with your name and number on the walls
- white blue tack to hang them will be provided (by the tag)
Poster ASSESSMENT
The poster assessment will be is divided in 2 sub-session over lunch:
GROUP A – POSTER 1 to 6
13:15-13:45
GROUP B – POSTER 7 to 12
13:45-14:15
Please be at your poster to present it for all 30 minutes.
BEM 2019 _event pictures
POSTER SESSION &LUNCH networking
Organizer supporters
SPONSORS
The Bristol ENDOTHELIAL meeting 2019 is sponsorized by the FACULTY of Life Science and BHI
PRIZES_PICS
